Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104138 | 0.72 | KDM4E (0.45) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL12657240 | 0.70 | MEN1 (0.63) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28385314 | 0.68 | MAPT (0.38) | KDM4EHTTALDH1A1MAPTPOLB | |
| SCHEMBL17911706 | 0.67 | KMT2A (0.59) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10104049 | 0.67 | RAB9A (0.55) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| Iodide SCHEMBL7031948 | 0.66 | KMT2A (0.62) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14393529 | 0.65 | RAB9A (0.56) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL22851946 | 0.65 | MEN1 (0.53) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL7568952 | 0.63 | KMT2A (0.67) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9588524 | 0.63 | RAB9A (0.67) | KDM4EKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051917-A9 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA SA (FR) | 2005-09-29 | — | — | WO | disclosed |