Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527456 | 0.91 | KCNH2 (0.73) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL6532956 | 0.87 | KCNH2 (0.58) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8331712 | 0.83 | KCNH2 (0.71) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL6949214 | 0.82 | KCNH2 (0.48) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL10572298 | 0.82 | KCNH2 (0.61) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL9158316 | 0.81 | ALDH1A1 (0.63) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL9158722 | 0.79 | KCNH2 (0.67) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL9373032 | 0.79 | KCNH2 (0.81) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL6499632 | 0.78 | KCNH2 (0.80) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8570458 | 0.78 | KCNH2 (0.71) | KCNH2KDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |