Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082980 | 0.86 | TBXAS1 (0.47) | GAAMAPTMAPK14CYP1A2CYP3A4 | |
| SCHEMBL1082601 | 0.80 | BRD4 (0.43) | KDM4EALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3802744 | 0.78 | KDM4E (0.50) | KDM4ERCE1GAAALDH1A1KMT2A | |
| SCHEMBL3807625 | 0.76 | SMN1; SMN2 (0.50) | KDM4EGAAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1082816 | 0.76 | KDM4E (0.38) | KDM4ERCE1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1082512 | 0.76 | KDM4E (0.38) | KDM4ERCE1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1082160 | 0.75 | KDM4E (0.37) | KDM4ERCE1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL26169830 | 0.73 | KMT2A (0.42) | KDM4ERCE1GAAALDH1A1KMT2A | |
| SCHEMBL17025614 | 0.73 | KMT2A (0.43) | KDM4ERCE1GAAALDH1A1KMT2A | |
| SCHEMBL1081505 | 0.72 | KMT2A (0.41) | KDM4EGAAALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |