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Sugi Predict / Compounds / SCHEMBL6532270

SCHEMBL6532270

SCHEMBL6532270

CCN1C(=NOC)Cc2cc(N3CC(CNC(C)=O)OC3=O)ccc21

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 5/20 0.53
▸ MAOB P27338 3/20 0.53
▸ PTGS1 P23219 2/20 0.53
▸ SDHA P31040 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ CALML3 P27482 1/20 0.53
▸ F10 P00742 4/20 0.42
▸ TOP2B Q02880 1/20 0.41
▸ ABCB11 O95342 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6532265 1.00 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6528116 0.91 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6528119 0.91 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6531171 0.89 MAOA (0.56) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6531173 0.89 MAOA (0.56) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6530438 0.87 MAOA (0.52) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6530440 0.87 MAOA (0.52) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5113213 0.86 MAOA (0.59) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5113218 0.86 MAOA (0.59) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6506477 0.83 MAOA (0.55) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082900-A2 OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-09-09 — — WO disclosed