Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887619 | 0.85 | HTR6 (0.68) | HTR6 | |
| SCHEMBL3886434 | 0.82 | HTR6 (0.67) | HTR6 | |
| SCHEMBL3894326 | 0.78 | HTR6 (0.78) | HTR6 | |
| SCHEMBL3953047 | 0.70 | HTR6 (0.57) | HTR6 | |
| SCHEMBL3889828 | 0.68 | HTR6 (0.51) | HTR6 | |
| SCHEMBL3889026 | 0.68 | HTR6 (0.81) | HTR6 | |
| Hydrochloric Acid SCHEMBL3886430 | 0.67 | HTR6 (0.98) | HTR6 | |
| SCHEMBL3899857 | 0.67 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3897408 | 0.67 | HTR6 (0.86) | HTR6 | |
| SCHEMBL5785029 | 0.66 | HTR6 (0.84) | HTR6CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509522-A1 | 1-(AMINOALKYL)-3-SULFONYLAZAINDOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth, A Corporation of the State of Delaware (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003101990-A1 | 1-(AMINOALKYL)-3-SULFONYLAZAINDOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2003-12-11 | — | — | WO | claimed |