Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SI | P14410 | 3/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GYS1 | P13807 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529006 | 0.85 | S1PR1 (0.44) | S1PR1S1PR3 | |
| SCHEMBL6531218 | 0.85 | SLC13A5 (0.41) | SLC13A5 | |
| SCHEMBL6529853 | 0.78 | SLC13A5 (0.39) | SLC13A5MAPTMAPK1FFAR4 | |
| SCHEMBL6529144 | 0.76 | S1PR1 (0.45) | S1PR1S1PR3FFAR1SLC13A5 | |
| SCHEMBL6532394 | 0.76 | PDE4A (0.41) | FFAR1MGAMGAASIMGAM2 | |
| SCHEMBL6530516 | 0.73 | SLC13A5 (0.53) | S1PR1S1PR3SLC13A5 | |
| SCHEMBL18411548 | 0.73 | GAA (0.65) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL6500410 | 0.72 | ACACB (0.42) | S1PR1GAAMAPTNPSR1 | |
| SCHEMBL6502428 | 0.72 | FFAR1 (0.44) | FFAR1SLC13A5 | |
| SCHEMBL6532174 | 0.71 | PDE4A (0.45) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |