Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | FSHR | P23945 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529533 | 0.85 | S1PR1 (0.56) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL6530123 | 0.85 | S1PR1 (0.56) | PTPN11PTPN1PTPN6S1PR1S1PR3 | |
| SCHEMBL6529006 | 0.85 | S1PR1 (0.44) | PTPN11S1PR1CNR2S1PR4S1PR3 | |
| SCHEMBL6529233 | 0.85 | S1PR1 (0.41) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL6504731 | 0.84 | S1PR1 (0.47) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6527018 | 0.81 | RARB (0.41) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6530176 | 0.81 | S1PR1 (0.45) | PTPN11S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6530516 | 0.80 | SLC13A5 (0.53) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6506651 | 0.80 | S1PR1 (0.45) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL6530994 | 0.80 | S1PR1 (0.43) | PTPN11S1PR1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |