Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.63 |
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531865 | 0.86 | SCN9A (0.51) | SCN9ADHODHCYP2C9MEN1KMT2A | |
| SCHEMBL725497 | 0.86 | CYP2C9 (0.53) | SCN9ACYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL7462078 | 0.82 | PARP1 (0.53) | SCN9APOLBPKMPARP1PARP2 | |
| SCHEMBL18704454 | 0.82 | SCN9A (0.53) | SCN9APOLBCYP2C9MEN1KMT2A | |
| SCHEMBL27944386 | 0.76 | PARP1 (0.46) | SCN9APOLBCYP2C9MEN1KMT2A | |
| SCHEMBL27787455 | 0.75 | SCN9A (0.47) | SCN9ADHODHCYP2C9MEN1KMT2A | |
| SCHEMBL5359936 | 0.74 | SCN9A (0.73) | SCN9ASCN10ACYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL5962999 | 0.73 | SCN9A (0.51) | SCN9ACYP2C9KMT2AALDH1A1MGLL | |
| SCHEMBL14277962 | 0.73 | RAB9A (0.49) | MPOTPOCYP3A4MEN1KMT2A | |
| SCHEMBL27648515 | 0.73 | F7 (0.46) | SCN9ACYP3A4KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |