SCHEMBL6532441

SCHEMBL6532441

CC1=CC2=CC(=O)C(C3CCCC3)=CC2=C1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
PTPN1 P18031 2/20 0.39
PTPRC P08575 1/20 0.38
PTPRF P10586 1/20 0.38
CDC25B P30305 1/20 0.38
APLNR P35414 2/20 0.37
NR1I2 O75469 1/20 0.30
KDM4B O94953 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30
DOHH Q9BU89 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781942 0.75 MAOA (0.64) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL30770693 0.75 MAOA (0.53) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL30770696 0.73 MAOA (0.52) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL10782026 0.73 MAOA (0.52) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL9273561 0.66 MAOA (1.00) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL8749597 0.65 MAOA (0.52) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL9343961 0.64 MAOA (0.96) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL29266041 0.64 MAOA (0.96) MAOAMAOBPTPN1PTPRCPTPRF
SCHEMBL7196898 0.64
SCHEMBL31495253 0.63 PTPN1 (0.46) MAOAMAOBPTPN1PTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6908974-B2 Catalyst composition and a process for preparing linear, isotactic polymers RIEGER BERNHARD (DE) 2005-06-21 US disclosed
US-6790922-B2 OLEFIN HOMO/COPOLYMERS, FORMED BY GAS PHASE POLYMERIZATION IN THE PRESENCE OF POLYMERIZATION CATALYSTS AND ACTIVATORS, USED AS FIBERS, SHEETS AND MOLDINGS HAVING IMPACT STRENGTH Rieger, Bernhard (DE) 2004-09-14 US disclosed
US-20030176612-A1 Linear, isotactic polymers, process for preparing same, and use thereof RIEGER BERNHARD (DE) 2003-09-18 US disclosed
US-6576726-B1 Titanium, zirconium, hafnium, vanadium, niobium, or tantalum metal cyclopentylindenyl complex and alumoxane activator RIEGER BERNHARD (DE) 2003-06-10 US disclosed
US-6555643-B1 Linear, isotactic polymers, process for preparing same, and use thereof RIEGER BERNHARD (DE) 2003-04-29 US disclosed