Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527651 | 0.88 | GRM5 (0.42) | GRM5GRM1DRD2DRD4DRD3 | |
| SCHEMBL6529962 | 0.83 | GRM5 (0.39) | GRM5GRM1DRD2DRD4DRD3 | |
| SCHEMBL6532170 | 0.76 | BTK (0.33) | GRM5GRM1BTK | |
| SCHEMBL6532581 | 0.72 | GRM5 (0.38) | GRM5GRM1BTK | |
| SCHEMBL6532521 | 0.69 | NOTUM (0.46) | GRM5GRM1BTK | |
| SCHEMBL6533438 | 0.69 | GRM5 (0.38) | GRM5GRM1BTK | |
| SCHEMBL6529963 | 0.69 | GRM5 (0.37) | GRM5GRM1BTK | |
| SCHEMBL6530325 | 0.67 | GRM1 (0.58) | GRM5GRM1 | |
| SCHEMBL6529525 | 0.67 | GRM1 (0.55) | GRM5GRM1 | |
| SCHEMBL1901516 | 0.66 | GRM5 (0.61) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |