SCHEMBL6532170

SCHEMBL6532170

CC1(C)OCC(C(=O)N2CC=C(c3c(F)cc(-n4cc(CC(S)C(N)=O)nn4)cc3F)CC2)O1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BTK Q06187 3/20 0.33
GRM1 Q13255 3/20 0.32
GRM5 P41594 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6532166 0.86 GRM1 (0.32) BTKGRM1GRM5
SCHEMBL6530570 0.82 GRM1 (0.34) GRM1GRM5
SCHEMBL6532589 0.76 GRM5 (0.40) BTKGRM1GRM5
SCHEMBL6532521 0.73 NOTUM (0.46) BTKGRM1GRM5
SCHEMBL5833336 0.72 CALML3 (0.40)
SCHEMBL6531972 0.72 NOTUM (0.38)
SCHEMBL4016425 0.71 MAOA (0.48)
SCHEMBL6532169 0.71
SCHEMBL5233720 0.70 MAOA (0.49)
SCHEMBL5833988 0.69 MAOA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082892-A2 TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2005-09-09 WO disclosed