Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096635 | 1.00 | HSD11B1 (0.43) | HSD11B1TDP1SYKL3MBTL1KDM4E | |
| SCHEMBL3000802 | 0.91 | TDP1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL4239498 | 0.91 | TDP1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL6523977 | 0.91 | TDP1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL5110954 | 0.90 | HSD11B1 (0.46) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL5111124 | 0.90 | HSD11B1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL5097380 | 0.89 | TDP1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL5111110 | 0.89 | TDP1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL5100460 | 0.89 | HSD11B1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL5103745 | 0.88 | TDP1 (0.42) | HSD11B1TDP1L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |