Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.46 |
| ▸ | PPARA | Q07869 | 14/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532720 | 1.00 | PPARG (0.46) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6532682 | 0.93 | LTA4H (0.43) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6532687 | 0.93 | LTA4H (0.43) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6532611 | 0.93 | PPARG (0.51) | PPARGPPARAMMEACECPA1 | |
| SCHEMBL6532606 | 0.93 | PPARG (0.51) | PPARGPPARAMMEACECPA1 | |
| SCHEMBL6533022 | 0.93 | PPARG (0.46) | PPARGPPARASMN1; SMN2MAOB | |
| SCHEMBL6533027 | 0.93 | PPARG (0.46) | PPARGPPARASMN1; SMN2MAOB | |
| SCHEMBL6533743 | 0.93 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL6533745 | 0.93 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL6533728 | 0.92 | PPARG (0.47) | PPARGPPARASMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |