Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CD4 | P01730 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581772 | 0.91 | MAPT (0.66) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL2581381 | 0.85 | MAPT (0.49) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL1386508 | 0.85 | MAPT (0.49) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL2577846 | 0.85 | MAPT (0.59) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL1383980 | 0.82 | MAPT (0.54) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL1385307 | 0.80 | MAPT (0.54) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL2578324 | 0.80 | MAPT (0.54) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL2580618 | 0.79 | ALDH1A1 (0.48) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL2575771 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL1387086 | 0.78 | MAPT (0.49) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051917-A9 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA SA (FR) | 2005-09-29 | — | — | WO | claimed |