Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950499 | 0.86 | ALDH1A1 (0.56) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6840351 | 0.85 | ALDH1A1 (0.72) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL14906562 | 0.81 | DAO (0.53) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2162146 | 0.81 | MAPT (0.50) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6840417 | 0.79 | ALDH1A1 (0.50) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL15183122 | 0.77 | CNR2 (0.48) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1759317 | 0.77 | ALDH1A1 (0.52) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29670373 | 0.77 | ALDH1A1 (0.52) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL25432803 | 0.77 | EPHX2 (0.59) | ALDH1A1KMT2AB3GNT2SMN1; SMN2LMNA | |
| SCHEMBL5320024 | 0.76 | ALDH1A1 (0.58) | GAAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058304-A1 | IMPLANTABLE DEVICE CONTAINING INHIBITOR OF MACROPHAGE MIGRATION INHIBITORY FACTOR | CORTICAL PTY LTD (AU) | 2005-06-30 | — | — | WO | disclosed |