SCHEMBL6533057

SCHEMBL6533057

NC(=O)C([SiH3])Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1669878 0.75
SCHEMBL449716 0.75
SCHEMBL16401948 0.72 CYP2C19 (0.44)
SCHEMBL380421 0.72
SCHEMBL10892230 0.69
Ammonia Solution, Strong SCHEMBL9801972 0.69
SCHEMBL310693 0.69
SCHEMBL1771381 0.69
SCHEMBL3911470 0.69
SCHEMBL5040518 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050032084-A1 Method of attaching a biopolymer to a solid support DUKE UNIVERSITY (US) 2005-02-10 US disclosed
EP-1210356-B1 METHOD FOR ANCHORING OLIGONUCLEOTIDES TO A SUBSTRATE AMERSHAM BIOSCIENCES CORP (US) 2004-10-27 EP disclosed
US-6528319-B1 Attachment of hairpin-shaped oligonucleotide primers containing multilple thiophosphate reaction sites to bromoacetamide derivatized silane glass; genetic probes, immunoassay AMERSHAM BIOSCIENCES CORP 2003-03-04 US disclosed
EP-1257662-A2 METHOD FOR DETECTING MUTATIONS USING ARRAYED PRIMER EXTENSION Amersham Biosciences Corp. (US) 2002-11-20 EP disclosed
US-6448010-B1 DETECTING A MUTATION IN A TARGET NUCLEIC ACID SEQUENCE THAT COMPRISES ATTACHING OLIGONUCLEOTIDE PRIMERS TO A SUBSTRATE, WHEREIN THE OLIGONUCLEOTIDE PRIMERS HAVE A SEQUENCE THAT IS COMPLEMENTARY TO THE TARGET NUCLEIC ACID SEQUENCE, AND WHEREIN AMERSHAM PHARMACIA BIOTECH, INC. 2002-09-10 US disclosed
US-20020076832-A1 Method of attaching a biopolymer to a solid support DUKE UNIVERSITY 2002-06-20 US disclosed
EP-1210356-A2 METHOD FOR ANCHORING OLIGONUCLEOTIDES TO A SUBSTRATE Amersham Biosciences Corp. (US) 2002-06-05 EP disclosed
WO-2001025485-A2 METHOD FOR DETECTING MUTATIONS USING ARRAYED PRIMER EXTENSION AMERSHAM BIOSCIENCES CORP (US) 2001-04-12 WO disclosed
WO-2001016152-A2 METHOD FOR ANCHORING OLIGONUCLEOTIDES TO A SUBSTRATE AMERSHAM PHARMACIA BIOTECH, INC. (US) 2001-03-08 WO disclosed