Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.62 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.59 |
| ▸ | PRKACA | P17612 | 2/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.59 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.59 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.59 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | PRKCG | P05129 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | LYN | P07948 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819564 | 0.77 | MAPK14 (0.74) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL28489978 | 0.77 | MAPK14 (0.71) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| Vk-19911 SCHEMBL140202 | 0.77 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL3670036 | 0.75 | MAPK14 (0.64) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| Sb-220025 SCHEMBL173441 | 0.74 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL7136557 | 0.74 | MAPK14 (0.77) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL6420895 | 0.74 | MAPK14 (0.70) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL4585589 | 0.74 | MAPK14 (0.80) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| Sb-242235 SCHEMBL2267209 | 0.74 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL1640317 | 0.73 | MAPK14 (0.75) | MAPK14MAPK11MAPK13MAPK12PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030091-A2 | STENTS AND INTRA-LUMINAL PROSTHESES CONTAINING MAP KINASE INHIBITORS | SCIOS INC. (US) | 2005-04-07 | — | — | WO | disclosed |