⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287855 | 0.98 | HTT (0.46) | — | |
| SCHEMBL7940754 | 0.98 | HTT (0.46) | — | |
| SCHEMBL11427894 | 0.98 | HTT (0.46) | — | |
| SCHEMBL9696541 | 0.92 | — | — | |
| SCHEMBL2043658 | 0.81 | — | — | |
| SCHEMBL1814059 | 0.78 | TSHR (0.59) | — | |
| SCHEMBL19562053 | 0.78 | TSHR (0.59) | — | |
| SCHEMBL8755575 | 0.78 | TSHR (0.52) | — | |
| Water SCHEMBL2360183 | 0.78 | THRB (0.62) | — | |
| Water SCHEMBL28885896 | 0.78 | THRB (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | claimed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | claimed |
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Apollo Therapeutics Limited (GB) | 2023-08-10 | — | — | US | disclosed |
| US-20180021277-A1 | ANTI-VIRULENCE COMPOSITIONS AND METHODS | CASE WESTERN RESERVE UNIVERSITY | 2018-01-25 | — | — | US | disclosed |
| US-9782363-B2 | Anti-virulance compositions and methods | CASE WESTERN RESERVE UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |
| US-20150265550-A1 | ANTI-VIRULANCE COMPOSITIONS AND METHODS | CASE WESTERN RESERVE UNIVERSITY | 2015-09-24 | — | — | US | disclosed |
| US-6903101-B1 | Substituted pyridazines and fused pyridazines with angiogenesis inhibiting activity | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-06-07 | — | — | US | disclosed |
| EP-1208096-B1 | SUBSTITUTED PYRIDAZINES AND FUSED PYRIDAZINES WITH ANGIOGENESIS INHIBITING ACTIVITY | BAYER AG (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1208096-A1 | SUBSTITUTED PYRIDAZINES AND FUSED PYRIDAZINES WITH ANGIOGENESIS INHIBITING ACTIVITY | Bayer Corporation (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | disclosed |
| WO-2001010859-A1 | SUBSTITUTED PYRIDAZINES AND FUSED PYRIDAZINES WITH ANGIOGENESIS INHIBITING ACTIVITY | BAYER CORPORATION (US) | 2001-02-15 | — | — | WO | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |
| US-4652666-A | PLANT SAFENING AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0100764-B1 | PROCESS FOR REMOVAL OF CARBON OXIDES FROM GAS MIXTURES | MONSANTO COMPANY (US) | 1986-06-04 | — | — | EP | disclosed |
| EP-0100764-A1 | Process for removal of carbon oxides from gas mixtures | MONSANTO COMPANY (US) | 1984-02-15 | — | — | EP | disclosed |