SCHEMBL653345

SCHEMBL653345

C=CC=C(C#N)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17180032 1.00
SCHEMBL653344 1.00
Ethylene Glycol SCHEMBL10359422 0.91 EGFR (0.35)
SCHEMBL7571820 0.91 EGFR (0.35)
SCHEMBL7571826 0.91 EGFR (0.35)
SCHEMBL9366538 0.84 EGFR (0.36)
SCHEMBL9366532 0.84 EGFR (0.36)
Propylene Glycol SCHEMBL10359448 0.83 TDP1 (0.34)
Di(Hydroxyethyl)Ether SCHEMBL10359459 0.83 TSHR (0.34)
SCHEMBL22056323 0.81 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116080157-B Copper foil-coated epoxy glass fiber laminated board for printed circuit 广东威世新材料有限公司 2023-08-04 CN claimed
CN-116080157-A Copper foil-coated epoxy glass fiber laminated board for printed circuit 广东威世新材料有限公司 2023-05-09 CN claimed
EP-3423499-B1 PHOTOCURABLE ELECTRON DEFICIENT OLEFIN-CONTAINING COMPOSITIONS Henkel IP & Holding GmbH (DE) 2022-06-01 EP claimed
CN-108884181-B Photocurable compositions containing electron poor olefins 汉高知识产权控股有限责任公司 2021-05-11 CN claimed
US-10941225-B2 Photocurable electron deficient olefin-containing compositions Henkel IP & Holding GmbH (DE) 2021-03-09 US claimed
US-10927071-B2 Process for preparing electron deficient olefins Henkel IP & Holding GmbH (DE) 2021-02-23 US claimed
EP-3558934-A1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS Henkel IP & Holding GmbH (DE) 2019-10-30 EP claimed
US-20190292141-A1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS HENKEL AG & CO. KGAA (DE) 2019-09-26 US claimed
EP-3423499-A1 PHOTOCURABLE ELECTRON DEFICIENT OLEFIN-CONTAINING COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-01-09 EP claimed
US-20180371124-A1 PHOTOCURABLE ELECTRON DEFICIENT OLEFIN-CONTAINING COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2018-12-27 US claimed
US-7569719-B1 Method of preparing electron deficient olefins LOCTITE (R&D) LIMITED (IE) 2009-08-04 US claimed
WO-2009053482-A2 ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM LOCTITE (R & D) LIMITED (IE) 2009-04-30 WO claimed
WO-2008050313-A1 IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS LOCTITE (R & D) LIMITED (IE) 2008-05-02 WO claimed
US-6607631-B1 Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an CLOSURE MEDICAL CORPORATION 2003-08-19 US claimed
WO-2002020684-A2 ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO claimed
US-6291544-B1 STORAGE STABILITY; FOR BONDING METALS, PLASTICS, RUBBERS, GLASS, WOOD, PAPER, LIVE, SOFT OR BONE TISSUE CHEMENCE, INC. 2001-09-18 US claimed
EP-0929617-A1 CYANOACRYLATE ADHESIVE Henkel Kommanditgesellschaft auf Aktien (DE) 1999-07-21 EP claimed
WO-1998014526-A1 CYANOACRYLATE ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-04-09 WO claimed
EP-0404446-B1 A method of forming photoresists by polymerisation of di-unsaturated monomers LOCTITE IRELAND LTD (IE) 1995-04-26 EP claimed
US-5386047-A Monomers for heat resistant, high bonding strength cyanoacrylate adhesives LOCTITE CORPORATION (US) 1995-01-31 US claimed