Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530931 | 0.78 | GAA (0.38) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL3262704 | 0.76 | CHRNB2 (0.35) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL7417993 | 0.72 | HTT (0.38) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL7328573 | 0.68 | GAA (0.40) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL10956440 | 0.67 | CHRNB2 (0.38) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL2422039 | 0.67 | GAA (0.42) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL11296604 | 0.67 | CHRNB2 (0.38) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL10965978 | 0.67 | CHRNB2 (0.38) | CHRNB2CHRNA4GAAALPGGFER | |
| SCHEMBL4790055 | 0.65 | CHRM1 (0.51) | — | |
| SCHEMBL1950582 | 0.65 | CHRNB2 (0.37) | CHRNB2CHRNA4GAAALPGGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099718-B1 | Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam | AIR PROD & CHEM (US) | 2005-03-30 | — | — | EP | claimed |
| US-6248801-B1 | CELL OPENING ADJUVANTS | AIR PRODUCTS AND CHEMICALS, INC. | 2001-06-19 | — | — | US | claimed |
| EP-1099718-A2 | Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-05-16 | — | — | EP | claimed |
| EP-1099718-B1 | Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam | AIR PROD & CHEM (US) | 2005-03-30 | — | — | EP | disclosed |
| US-6248801-B1 | CELL OPENING ADJUVANTS | AIR PRODUCTS AND CHEMICALS, INC. | 2001-06-19 | — | — | US | disclosed |
| EP-1099718-A2 | Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-05-16 | — | — | EP | disclosed |