Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476456 | 0.89 | PTGDR2 (0.72) | PTGDR2AKR1B1 | |
| SCHEMBL1386959 | 0.87 | PTGDR2 (0.54) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5438307 | 0.85 | PTGDR2 (0.60) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1386979 | 0.83 | PTGDR2 (1.00) | PTGDR2AKR1B1CYP2C9PTGS1 | |
| SCHEMBL5477529 | 0.82 | PTGDR2 (0.62) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5428186 | 0.79 | PTGDR2 (0.61) | PTGDR2CYP2C9 | |
| SCHEMBL5474079 | 0.79 | PTGDR2 (0.63) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5473428 | 0.78 | PTGDR2 (0.57) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5474051 | 0.78 | PTGDR2 (0.56) | PTGDR2AKR1B1 | |
| SCHEMBL5479480 | 0.77 | PTGDR2 (0.56) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551802-A1 | INDOLE-3-SULPHUR DERIVATIVES | AstraZeneca AB (SE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004007451-A1 | INDOLE-3-SULPHUR DERIVATIVES | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |