SCHEMBL6533659

SCHEMBL6533659

C=C(C)C(=O)OC(N)CN

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28182717 0.84 TSHR (0.43) TSHRALDH1A1THRBTDP1
SCHEMBL6267210 0.83 TSHR (0.39) TSHRALDH1A1THRBTDP1
SCHEMBL26525 0.83 TSHR (0.42) TSHRALDH1A1THRBTDP1
SCHEMBL27440339 0.83 TSHR (0.42) TSHRALDH1A1THRBTDP1
Hydrochloric Acid SCHEMBL509077 0.81 TSHR (0.41) TSHRALDH1A1THRBTDP1
SCHEMBL7528585 0.80 TSHR (0.43) TSHRALDH1A1THRBTDP1
SCHEMBL2597658 0.80 TSHR (0.43) TSHRALDH1A1THRBTDP1
SCHEMBL1033366 0.79 ALDH1A1 (0.43) TSHRALDH1A1THRBTDP1
SCHEMBL4835666 0.79 TSHR (0.39) TSHRALDH1A1THRBTDP1
SCHEMBL11444741 0.79 TSHR (0.59) TSHRALDH1A1THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101824314-B Terpolymer oil soluble viscosity reducer for thick oil exploration and transportation and preparation method thereof UNIV CHINA GEOSCIENCES WUHAN 2013-05-08 CN disclosed
CN-101824314-A Terpolymer oil soluble viscosity reducer for thick oil exploration and transportation and preparation method thereof UNIV CHINA GEOSCIENCES WUHAN 2010-09-08 CN disclosed
US-20050008828-A1 Patterned polymer microgel and method of forming same TRUSTEES OF STEVENS INSTITUTE OF TECHNOLOGY 2005-01-13 US disclosed
US-20040137039-A1 Methods for controlled release of molecules from layered polymer films TRUSTEES OF STEVENS INSTITUTE OF TECHNOLOGY 2004-07-15 US disclosed