Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393821 | 0.96 | MAPT (0.54) | MAPTRAB9ANPC1KMT2APOLB | |
| Methylamine SCHEMBL27075697 | 0.95 | MAPT (0.50) | MAPTRAB9ANPC1KMT2APOLB | |
| Methane SCHEMBL7696978 | 0.95 | MAPT (0.53) | MAPTRAB9ANPC1KMT2APOLB | |
| Ammonia Solution, Strong SCHEMBL27092164 | 0.95 | MAPT (0.53) | MAPTRAB9ANPC1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL10393362 | 0.95 | MAPT (0.53) | MAPTRAB9ANPC1KMT2APOLB | |
| SCHEMBL60465 | 0.84 | KMT2A (0.47) | MAPTRAB9ANPC1KMT2APOLB | |
| SCHEMBL1046632 | 0.83 | TDP1 (0.48) | MAPTRAB9ANPC1KMT2APOLB | |
| SCHEMBL9717935 | 0.82 | ATM (0.59) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL69865 | 0.81 | RAB9A (0.65) | MAPTRAB9ANPC1KMT2APOLB | |
| SCHEMBL31045928 | 0.81 | RAB9A (0.65) | MAPTRAB9ANPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171094-A1 | Pyrrolopyrimidine derivatives | TEIJIN, LIMITED (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20040266766-A1 | Selective urokinase inhibitors | WILEX AG (DE) | 2004-12-30 | — | — | US | disclosed |
| EP-1477490-A1 | PYRROLOPYRIMIDINE DERIVATIVE | TEIJIN LIMITED (JP) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266766-A1 | Selective urokinase inhibitors | PLAU, PLAUR, SERPINE1 | MAPT 3889/4885RAB9A 2546/4885NPC1 4425/4885 |
| US-20050171094-A1 | Pyrrolopyrimidine derivatives | GSK3B, GSK3A, GSKIP | MAPT 296/4885RAB9A 2170/4885NPC1 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.