Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 4/20 | 0.44 |
| ▸ | RAD1 | O60671 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LTA | P01374 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533773 | 1.00 | RAD51 (0.44) | RAD51RAD1P2RY6ENPP2APEX1 | |
| SCHEMBL10622332 | 0.83 | APEX1 (0.47) | RAD51RAD1P2RY6ENPP2APEX1 | |
| SCHEMBL2834143 | 0.81 | RAD1 (0.51) | RAD51RAD1P2RY6APEX1ALDH1A1 | |
| SCHEMBL156114 | 0.80 | RAD1 (0.50) | RAD51RAD1P2RY6APEX1ALDH1A1 | |
| SCHEMBL30727492 | 0.79 | P2RY6 (0.63) | RAD51RAD1P2RY6ENPP2APEX1 | |
| SCHEMBL3130034 | 0.79 | P2RY6 (0.63) | RAD51RAD1P2RY6ENPP2APEX1 | |
| Acridine SCHEMBL5792145 | 0.75 | RAD1 (0.53) | RAD51RAD1P2RY6ENPP2APEX1 | |
| Acridine SCHEMBL6039596 | 0.75 | RAD1 (0.53) | RAD51RAD1P2RY6ENPP2APEX1 | |
| SCHEMBL5364759 | 0.74 | RAD1 (0.51) | RAD51RAD1P2RY6APEX1ALDH1A1 | |
| SCHEMBL344713 | 0.74 | RAD1 (0.51) | RAD51RAD1P2RY6APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032056-A1 | Using conserved transcribed but nontranslated sequences to identify polymorphism in grass plant genomes; gene expression analysis and restriction fragment length polymorphism | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-10 | — | — | US | disclosed |