Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635306 | 0.70 | MAPK14 (0.57) | MAPK14MAPKAPK2 | |
| SCHEMBL4382819 | 0.69 | MAPK14 (0.50) | MAPK14MAPK11 | |
| SCHEMBL4384896 | 0.68 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL13602931 | 0.68 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL4381554 | 0.68 | MAPK14 (0.51) | MAPK14 | |
| Hydrochloric Acid SCHEMBL4376642 | 0.68 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL13610862 | 0.68 | MAPK14 (0.55) | MAPK14 | |
| Hydrochloric Acid SCHEMBL4379526 | 0.68 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL4382455 | 0.67 | MAPK14 (0.48) | MAPK14MAPKAPK2 | |
| SCHEMBL4379497 | 0.67 | MAPK14 (0.50) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |