Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528205 | 0.80 | AAK1 (0.70) | AAK1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL23524938 | 0.78 | ALDH1A1 (0.52) | AAK1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL23524935 | 0.78 | ALDH1A1 (0.52) | AAK1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL23567966 | 0.78 | AAK1 (0.50) | AAK1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL13390947 | 0.77 | KMT2A (0.63) | KMT2AMEN1MAPK1L3MBTL1GAA | |
| SCHEMBL23525114 | 0.77 | AAK1 (0.48) | AAK1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL23525117 | 0.77 | AAK1 (0.48) | AAK1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL23524981 | 0.76 | AAK1 (0.47) | AAK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL23524984 | 0.76 | AAK1 (0.47) | AAK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8133166 | 0.75 | SERPINE1 (0.52) | ALDH1A1KMT2AMEN1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |