Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534107 | 1.00 | HPGD (0.45) | HPGDPTPN1KCNH2MAOAMAOB | |
| SCHEMBL10365494 | 0.84 | HPGD (0.61) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL10365493 | 0.84 | HPGD (0.61) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL8141922 | 0.80 | KCNH2 (0.50) | HPGDPTPN1KCNH2MAOAMAOB | |
| SCHEMBL8141923 | 0.80 | KCNH2 (0.50) | HPGDPTPN1KCNH2MAOAMAOB | |
| SCHEMBL10366704 | 0.79 | HPGD (0.61) | HPGDPIM1PIM2PPARGPPARA | |
| SCHEMBL10364994 | 0.79 | HPGD (0.61) | HPGDPIM1PIM2PPARGPPARA | |
| SCHEMBL10364971 | 0.79 | HPGD (0.61) | HPGDPIM1PIM2PPARGPPARA | |
| SCHEMBL9316768 | 0.77 | HPGD (0.48) | HPGDKCNH2POLBPIM1PIM3 | |
| SCHEMBL9316762 | 0.77 | HPGD (0.48) | HPGDKCNH2POLBPIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |