Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.51 |
| ▸ | PPARA | Q07869 | 17/20 | 0.51 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534115 | 1.00 | PPARG (0.51) | PPARGPPARAALKBH1MMEACE | |
| SCHEMBL6532611 | 0.93 | PPARG (0.51) | PPARGPPARAALKBH1MMEACE | |
| SCHEMBL6532813 | 0.93 | PPARG (0.53) | PPARGPPARAALKBH1MMEACE | |
| SCHEMBL6532807 | 0.93 | PPARG (0.53) | PPARGPPARAALKBH1MMEACE | |
| SCHEMBL6532606 | 0.93 | PPARG (0.51) | PPARGPPARAALKBH1MMEACE | |
| SCHEMBL6532442 | 0.93 | PPARG (0.56) | PPARGPPARAALKBH1GPR34 | |
| SCHEMBL6532450 | 0.93 | PPARG (0.56) | PPARGPPARAALKBH1GPR34 | |
| SCHEMBL6534150 | 0.89 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL6534152 | 0.89 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL6532104 | 0.87 | LTA4H (0.43) | PPARGPPARAMMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |