⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18600818 | 1.00 | — | — | |
| SCHEMBL51213 | 1.00 | — | — | |
| SCHEMBL16202107 | 1.00 | — | — | |
| SCHEMBL8767645 | 1.00 | — | — | |
| SCHEMBL8766836 | 1.00 | — | — | |
| SCHEMBL13941500 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL13020684 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL12923257 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL14845413 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL25739835 | 0.82 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417064-B2 | 3-aryloxy/thio-3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake | ELI LILLY AND COMPANY (US) | 2008-08-26 | — | — | US | disclosed |
| US-7410982-B2 | Propanamine derivatives as serotonin and norepinephrine reuptake inhibitors | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410996-B2 | 3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
| US-20040068068-A1 | Optically active polymer with epoxide functions, method for preparing same, and use thereof | UNIVERSITY CLAUDE BERNARD LYON 1 (FR) | 2004-04-08 | — | — | US | disclosed |
| EP-1341828-A1 | OPTICALLY ACTIVE POLYMER WITH EPOXIDE FUNCTIONS, METHOD FOR PREPARING SAME, AND USE THEREOF | University Claude Bernard Lyon I (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002042346-A1 | OPTICALLY ACTIVE POLYMER WITH EPOXIDE FUNCTIONS, METHOD FOR PREPARING SAME, AND USE THEREOF | UNIVERSITY CLAUDE BERNARD LYON I (FR) | 2002-05-30 | — | — | WO | disclosed |