⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37921 | 1.00 | — | — | |
| SCHEMBL30874993 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5838863 | 0.95 | — | — | |
| SCHEMBL1122022 | 0.95 | — | — | |
| SCHEMBL7593832 | 0.95 | — | — | |
| SCHEMBL9738638 | 0.95 | — | — | |
| Water SCHEMBL11593864 | 0.95 | — | — | |
| Bromide SCHEMBL8432007 | 0.95 | ALDH1A1 (0.36) | — | |
| SCHEMBL31401982 | 0.95 | — | — | |
| SCHEMBL6013271 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854878-A4 | SYNTHESIS OF GLYCOCONJUGATES OF THE LEWIS Y EPITOPE AND USES THEREOF | SLOAN KETTERING INST CANCER (US) | 2004-03-24 | — | — | EP | disclosed |
| US-6645935-B2 | De-silylating, to form an N-sulfonamide pentasaccharide; cleaving N-sulfonamide cleaving the N-sulfonamide pentasaccharide formed in to form a deprotected pentasaccharide; acetylating deprotected pentasaccharide | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2003-11-11 | — | — | US | disclosed |
| US-6544952-B1 | Useful as vaccines for inducing antibodies to epithelial cancer cells | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2003-04-08 | — | — | US | disclosed |
| US-20020038017-A1 | Synthesis of glycoconjugates of the lewis y epitope and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2002-03-28 | — | — | US | disclosed |
| US-6303120-B1 | INDUCING ANTIBODIES IN A SUBJECT TO AN ALLYL-SUBSTITUTED PENTASACCHARIDE BY ADMINISTERING THE COMPOUND CONJUGATED TO A PROTEIN CARRIER AT ITS ALLYL GROUP. | MEMORIAL SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2001-10-16 | — | — | US | disclosed |
| EP-0854878-A1 | SYNTHESIS OF GLYCOCONJUGATES OF THE LEWIS Y EPITOPE AND USES THEREOF | Sloan-Kettering Institute For Cancer Research (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997003995-A1 | SYNTHESIS OF GLYCOCONJUGATES OF THE LEWIS Y EPITOPE AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-02-06 | — | — | WO | disclosed |