Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1643309 | 0.90 | ALDH1A1 (0.84) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL15162 | 0.90 | — | — | |
| SCHEMBL8064669 | 0.90 | — | — | |
| Glycidol SCHEMBL27672258 | 0.89 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Ethyl Chloride SCHEMBL27548515 | 0.89 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL28182627 | 0.89 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL10425203 | 0.88 | — | — | |
| Fluoride SCHEMBL8522213 | 0.88 | — | — | |
| Ethylene SCHEMBL28860341 | 0.88 | ALDH1A1 (0.95) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| Methane SCHEMBL6049887 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180985-A1 | Tack free surface cures of polymers by organic peroxides in the presence of air | ARKEMA INC. | 2004-09-16 | — | — | US | disclosed |
| US-6747099-B1 | BIS-, TRI- AND HIGHER POLY-MALEIMIDES, SILICONE ELASTOMER, P-PHENYLENEDIAMINE BASED ANTIOZONANTS, SULFUR VULCANIZATION ACCELERANT | ATOFINA CHEMICALS, INC. | 2004-06-08 | — | — | US | disclosed |
| CN-1140552-C | Composition comprising a metal oxide and a metal oxide | �Ͼ���ҵ��ѧ | 2004-03-03 | — | — | CN | disclosed |
| CN-1130415-C | Porous film, process for producing the same, and laminate films and recording sheets made with the use porous film | DAICEL CHEM (JP) | 2003-12-10 | — | — | CN | disclosed |
| EP-1149122-A4 | TACK FREE SURFACE CURES OF POLYMERS BY ORGANIC PEROXIDES IN THE PRESENCE OF AIR | ATOFINA CHEM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6479560-B2 | Foaming compositions and methods for making and using the composition | DENOVUS LLC | 2002-11-12 | — | — | US | disclosed |
| CN-1336939-A | Tack-free surface curing of polymers by organic peroxides in the presence of air | ATOFINA CHEM INC (US) | 2002-02-20 | — | — | CN | disclosed |
| EP-1149122-A1 | TACK FREE SURFACE CURES OF POLYMERS BY ORGANIC PEROXIDES IN THE PRESENCE OF AIR | Atofina Chemicals, Inc. (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2001034680-A1 | TACK FREE SURFACE CURES OF POLYMERS BY ORGANIC PEROXIDES IN THE PRESENCE OF AIR | ATOFINA CHEMICALS, INC. (US) | 2001-05-17 | — | — | WO | disclosed |
| CN-1244874-A | Composition comprising a metal oxide and a metal oxide | NAT STARCH CHEM LTD (GB) | 2000-02-16 | — | — | CN | disclosed |
| CN-1214710-A | Porous film, process for producing the same, and laminate films and recording sheets made with the use porous film | DAICEL CHEM (JP) | 1999-04-21 | — | — | CN | disclosed |
| US-5070140-A | Copolymers of vinyl acetate and allyl glycidyl ether capped C12 -C.sub. | BASF CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |