Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842371 | 0.98 | TDP1 (0.39) | TDP1MEN1KMT2APTPN1L3MBTL1 | |
| SCHEMBL6209232 | 0.73 | ADH1C (0.36) | TSHR | |
| SCHEMBL6937746 | 0.73 | — | — | |
| SCHEMBL1467658 | 0.72 | TDP1 (0.31) | TDP1 | |
| SCHEMBL15726351 | 0.72 | PTPN1 (0.51) | TDP1MEN1KMT2APTPN1L3MBTL1 | |
| SCHEMBL4522063 | 0.71 | SLC22A6 (0.39) | TDP1MEN1KMT2APTPN1ALDH1A1 | |
| SCHEMBL8703050 | 0.71 | CA12 (0.41) | L3MBTL1ALDH1A1 | |
| SCHEMBL6938492 | 0.71 | CA14 (0.36) | TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL11655565 | 0.71 | TDP1 (0.56) | TDP1MEN1KMT2APTPN1L3MBTL1 | |
| SCHEMBL7659602 | 0.71 | TDP1 (0.56) | TDP1MEN1KMT2APTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941120-A4 | BRANCHED PEPTIDE LINKERS | BRISTOL MYERS SQUIBB CO (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-0941120-A1 | BRANCHED PEPTIDE LINKERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998019705-A1 | BRANCHED PEPTIDE LINKERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |