Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534854 | 1.00 | GAA (0.48) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL5667351 | 0.91 | MAPT (0.50) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL5667349 | 0.91 | MAPT (0.50) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL942292 | 0.86 | MAPT (0.61) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL30769484 | 0.86 | MAPT (0.61) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL942294 | 0.86 | MAPT (0.61) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL10899994 | 0.80 | MAPT (0.58) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL10899990 | 0.80 | MAPT (0.58) | GAAMAPTMAPK1HTTPOLB | |
| SCHEMBL1703027 | 0.78 | GAA (0.46) | GAAMAPTMAPK1HTTUSP2 | |
| SCHEMBL1703028 | 0.78 | GAA (0.46) | GAAMAPTMAPK1HTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073935-A4 | DUAL LAYER PHOTOCONDUCTORS WITH CHARGE GENERATION LAYER CONTAINING CHARGE TRANSPORT COMPOUND | LEXMARK INT INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1073935-A1 | DUAL LAYER PHOTOCONDUCTORS WITH CHARGE GENERATION LAYER CONTAINING CHARGE TRANSPORT COMPOUND | Lexmark International, Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999056181-A1 | DUAL LAYER PHOTOCONDUCTORS WITH CHARGE GENERATION LAYER CONTAINING CHARGE TRANSPORT COMPOUND | LEXMARK INTERNATIONAL, INC. (US) | 1999-11-04 | — | — | WO | disclosed |
| EP-0149914-B1 | OVERCOATED ELECTROPHOTOGRAPHIC IMAGING MEMBER | XEROX CORPORATION (US) | 1988-08-10 | — | — | EP | disclosed |