SCHEMBL1703028

SCHEMBL1703028

CCCCN(CCCC)c1ccc(C=NN(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
AR P10275 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
INSR P06213 1/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MCL1 Q07820 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
G6PC1 P35575 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ATG4B Q9Y4P1 1/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1703027 1.00 GAA (0.46) GAAMAPTMAPK1HTTAR
SCHEMBL1702641 0.91 MAPT (0.48) GAAMAPTMAPK1HTTMEN1
SCHEMBL1702640 0.91 MAPT (0.48) GAAMAPTMAPK1HTTMEN1
SCHEMBL122069 0.84 MAPT (0.61) GAAMAPTMAPK1HTTMEN1
SCHEMBL122070 0.84 MAPT (0.61) GAAMAPTMAPK1HTTMEN1
SCHEMBL332093 0.79 CYP1A2 (0.53) GAAMAPTMAPK1HTTMEN1
SCHEMBL332094 0.79 CYP1A2 (0.53) GAAMAPTMAPK1HTTMEN1
SCHEMBL107013 0.79 CNR2 (0.49) GAAMAPTARMEN1KMT2A
SCHEMBL7821079 0.78 MAPT (0.50) GAAMAPTMAPK1HTTMEN1
SCHEMBL7821078 0.78 MAPT (0.50) GAAMAPTMAPK1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP claimed
EP-0001599-A1 Electrophotographic recording material and its application in a copying process International Business Machines Corporation (US) 1979-05-02 EP claimed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US claimed
US-20150185627-A1 Method of Producing Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-20150185629-A1 Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-8178265-B2 Electrophotographic photoreceptor having a spectral marker and electrophotographic printer using the same LEXMARK INTERNATIONAL, INC. (US) 2012-05-15 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7955769-B2 Control of crazing, cracking or crystallization of a charge transport layer in a photoconductor LEXMARK INTERNATIONAL, INC. (US) 2011-06-07 US disclosed
US-20100167191-A1 Electrophotographic Photoreceptor Having a Spectral Marker and Electrophotographic Printer Using the Same BANK TRUST COMPANY, NATIONAL ASSOCIATION 2010-07-01 US disclosed
US-20090233196-A1 Photoconductors Containing Copper Phthalocyanine and Titanyl Phthalocyanine in the Charge Generation Layer LEXMARK INTERNATIONAL, INC. 2009-09-17 US disclosed
US-20090202928-A1 Control of Crazing, Cracking or Crystallization of a Charge Transport Layer in a Photoconductor BANK TRUST COMPANY, NATIONAL ASSOCIATION 2009-08-13 US disclosed
US-4921773-A Process for preparing an electrophotographic imaging member XEROX CORPORATION (US) 1990-05-01 US disclosed
US-4895783-A SOLVENT RESISTANCE, WEAR RESISTANCE XEROX CORPORATION (US) 1990-01-23 US disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4423129-A CHARGE TRANSFER COMPOUND CANON KABUSHIKI KAISHA (JP) 1983-12-27 US disclosed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP disclosed
EP-0001599-A1 Electrophotographic recording material and its application in a copying process International Business Machines Corporation (US) 1979-05-02 EP disclosed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US disclosed