Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782924 | 0.85 | LTA4H (0.55) | LTA4HALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1051397 | 0.81 | LTA4H (0.57) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL339500 | 0.81 | LTA4H (0.57) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| Alcohol SCHEMBL27353807 | 0.78 | LTA4H (0.53) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6799758 | 0.78 | NQO1 (0.52) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL4229019 | 0.78 | LTA4H (0.53) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL4960422 | 0.78 | LTA4H (0.53) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL28929724 | 0.78 | NQO1 (0.52) | LTA4HNQO1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL130818 | 0.77 | TRIM24 (0.57) | LTA4HALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7682786 | 0.76 | NQO1 (0.50) | LTA4HNQO1ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171437-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO | VERA THERAPEUTICS INC (US) | 2021-06-10 | — | — | US | disclosed |
| EP-1115739-A4 | AUXILIARY FOR AMIDE BOND FORMATION | UNIV QUEENSLAND (AU) | 2004-10-27 | — | — | EP | disclosed |
| EP-1115739-A1 | AUXILIARY FOR AMIDE BOND FORMATION | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018789-A1 | AUXILIARY FOR AMIDE BOND FORMATION | THE UNIVERSITY OF QUEENSLAND (AU) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171437-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO | TARBP1, TIA1, SSB | LTA4H 3555/4885NQO1 4713/4885ALDH1A1 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.