Chlorobenzene

Chlorobenzene

SCHEMBL6535065

Clc1ccccc1.NC(=O)NS(N)(=O)=O

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
FLT1 P17948 3/20 0.45
FLT4 P35916 3/20 0.45
KDR P35968 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
NPC1 O15118 2/20 0.42
TSHR P16473 1/20 0.42
EGFR P00533 1/20 0.41
ERBB2 P04626 1/20 0.41
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL7454781 0.79 TSHR (0.61) MEN1KMT2AFLT1FLT4KDR
Chlorobenzene SCHEMBL9576941 0.76 TSHR (0.65) MEN1KMT2AL3MBTL1NPC1TSHR
Chlorobenzene SCHEMBL10879665 0.76 TSHR (0.65) MEN1KMT2ACA1CA2TSHR
Chlorobenzene SCHEMBL27488158 0.76 TSHR (0.65) MEN1KMT2AL3MBTL1NPC1TSHR
SCHEMBL161898 0.76
Chlorobenzene SCHEMBL27868866 0.75 TSHR (0.50) MEN1KMT2AL3MBTL1NPC1TSHR
Chlorobenzene SCHEMBL27465656 0.74 TSHR (0.61) MEN1KMT2AFLT1FLT4KDR
Chlorobenzene SCHEMBL27634612 0.74 TSHR (0.61) MEN1KMT2AL3MBTL1NPC1TSHR
Chlorobenzene SCHEMBL7223075 0.73 TSHR (0.69) MEN1KMT2AFLT1FLT4KDR
Chlorobenzene SCHEMBL11092864 0.73 TSHR (0.52) MEN1KMT2AFLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011311-A4 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE EXSEED GENETICS L L C (US) 2004-05-26 EP claimed
EP-1011311-A1 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE Exseed Genetics L.L.C. (US) 2000-06-28 EP claimed
WO-1999007211-A9 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE EXSEED GENETICS L L C (US) 1999-04-29 WO claimed
WO-1999007211-A1 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE EXSEED GENETICS, L.L.C. (US) 1999-02-18 WO claimed