Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.45 |
| ▸ | PLA2G2E | Q9NZK7 | 3/20 | 0.45 |
| ▸ | PLA2G2F | Q9BZM2 | 2/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 2/20 | 0.44 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.44 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.44 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862301 | 0.92 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL818699 | 0.92 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL818695 | 0.91 | PLA2G2A (0.50) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL29862428 | 0.91 | PLA2G2A (0.50) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL8064581 | 0.91 | PLA2G2A (0.47) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL8062442 | 0.85 | PLA2G2A (0.58) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7968417 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7411643 | 0.84 | PLA2G2A (0.46) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7964297 | 0.84 | PLA2G2A (0.45) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7967330 | 0.84 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011670-A4 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | LILLY CO ELI (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1011670-A1 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | ELI LILLY AND COMPANY (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1999009978-A1 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | claimed |