Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576491 | 0.89 | LMNA (0.70) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL9576416 | 0.88 | LMNA (0.62) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL9576503 | 0.88 | LMNA (0.68) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL6724069 | 0.88 | LMNA (0.68) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL5317375 | 0.88 | LMNA (0.68) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL1070537 | 0.88 | LMNA (0.68) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL14297031 | 0.86 | LMNA (0.59) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL31632703 | 0.86 | LMNA (0.61) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL9576439 | 0.86 | LMNA (0.61) | NAAAFAAHLMNAL3MBTL1KMT2A | |
| SCHEMBL9576424 | 0.86 | LMNA (0.61) | NAAAFAAHLMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318806-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-01-21 | — | — | EP | claimed |
| EP-1318806-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002024197-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-03-28 | — | — | WO | claimed |
| EP-1318806-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-1318806-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024197-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-03-28 | — | — | WO | disclosed |