Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535125 | 0.84 | KDM4E (0.63) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL12538520 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL18958893 | 0.77 | HDAC1 (0.53) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL4419202 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL10349516 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL6535591 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL6535571 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL81318 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL81317 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL29636389 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HPGDALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011702-A4 | A METHOD FOR TREATING DIABETES, HYPERGLYCEMIA AND HYPOGLYCEMIA | RICEX COMPANY (US) | 2004-01-21 | — | — | EP | disclosed |
| US-6126943-A | BY INGESTING A STABILIZED RICE BRAN DERIVATIVE. | THE RICEX COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| EP-1011702-A1 | A METHOD FOR TREATING DIABETES, HYPERGLYCEMIA AND HYPOGLYCEMIA | The Ricex Company (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999011144-A1 | A METHOD FOR TREATING HYPERCHOLESTEROLEMIA, HYPERLIPIDEMIA, AND ATHEROSCLEROSIS | THE RICEX COMPANY, INC. (US) | 1999-03-11 | — | — | WO | disclosed |
| WO-1999010002-A1 | A METHOD FOR TREATING DIABETES, HYPERGLYCEMIA AND HYPOGLYCEMIA | THE RICEX COMPANY, INC. (US) | 1999-03-04 | — | — | WO | disclosed |