Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | PPARD | Q03181 | 7/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385594 | 0.77 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL6536576 | 0.77 | PPARG (0.56) | PPARGPPARAPPARDPOLBMAPT | |
| SCHEMBL6536575 | 0.75 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL6382723 | 0.73 | PPARG (0.62) | PPARGPPARAPPARDPTPRBMAPT | |
| SCHEMBL28512690 | 0.71 | PPARG (0.67) | PPARGPPARAPPARDPTPRB | |
| SCHEMBL20395690 | 0.71 | PPARG (0.67) | PPARGPPARAPPARDPTPRB | |
| SCHEMBL6382746 | 0.71 | PPARG (0.67) | PPARGPPARAPPARDPTPRBLTA4H | |
| SCHEMBL6704879 | 0.71 | PPARG (0.71) | PPARGPPARAPPARDPTPRBLTA4H | |
| SCHEMBL6383472 | 0.71 | PPARG (0.60) | PPARGPPARAPPARDPTPRB | |
| SCHEMBL5992953 | 0.71 | PPARG (0.63) | PPARGPPARAPPARDPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465858-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059864-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-07-24 | — | — | WO | disclosed |