Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.71 |
| ▸ | PPARD | Q03181 | 10/20 | 0.71 |
| ▸ | PPARA | Q07869 | 8/20 | 0.71 |
| ▸ | LDHA | P00338 | 1/20 | 0.63 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696075 | 0.95 | PPARG (0.66) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL28512690 | 0.88 | PPARG (0.67) | PPARGPPARDPPARAPTPRB | |
| SCHEMBL6382746 | 0.88 | PPARG (0.67) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL20395690 | 0.88 | PPARG (0.67) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL6688424 | 0.87 | LDHA (0.58) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL6688428 | 0.87 | LDHA (0.58) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL6484840 | 0.86 | PPARG (0.65) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL7033327 | 0.85 | PPARG (0.67) | PPARGPPARDPPARALTA4H | |
| SCHEMBL20395698 | 0.84 | PPARG (0.62) | PPARGPPARDPPARALDHAPTPRB | |
| SCHEMBL5402468 | 0.84 | PPARG (1.00) | PPARGPPARDPPARALDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113266-A1 | DERIVATIVES OF PHENYLALKYL AND PHENOXYALKYL ACIDS FOR THE TREATMENT OF THE HYPERGLYCAEMIA AND HYPERTRIGLYCERIDAEMIA AND TYPE 2 DIABETES AND PROCESS FOR PREPARING THEM | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-12-29 | — | — | WO | claimed |
| WO-2004113266-A1 | DERIVATIVES OF PHENYLALKYL AND PHENOXYALKYL ACIDS FOR THE TREATMENT OF THE HYPERGLYCAEMIA AND HYPERTRIGLYCERIDAEMIA AND TYPE 2 DIABETES AND PROCESS FOR PREPARING THEM | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-12-29 | — | — | WO | disclosed |