SCHEMBL6536458

SCHEMBL6536458

CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.64
PAM P19021 2/20 0.58
MAPT P10636 2/20 0.55
TSHR P16473 1/20 0.55
LMNA P02545 4/20 0.53
DNM1 Q05193 1/20 0.53
ALDH1A1 P00352 1/20 0.53
KDM4E B2RXH2 1/20 0.51
DUSP3 P51452 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
PRKCA P17252 1/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
MAPK1 P28482 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084720 1.00 DGKA (0.64) DGKAPAMMAPTTSHRLMNA
SCHEMBL4331049 1.00 DGKA (0.64) DGKAPAMMAPTTSHRLMNA
SCHEMBL3161151 1.00 DGKA (0.64) DGKAPAMMAPTTSHRLMNA
SCHEMBL4624636 1.00 DGKA (0.64) DGKAPAMMAPTTSHRLMNA
SCHEMBL13073330 1.00 DGKA (0.64) DGKAPAMMAPTTSHRLMNA
SCHEMBL5709908 1.00 DGKA (0.64) DGKAPAMMAPTTSHRLMNA
Ammonia Solution, Strong SCHEMBL6749467 0.98 DGKA (0.62) DGKAPAMMAPTTSHRLMNA
SCHEMBL245738 0.98 DGKA (0.61) DGKAPAMMAPTTSHRLMNA
Ethylene Glycol SCHEMBL9815228 0.94 DGKA (0.58) DGKAPAMMAPTTSHRLMNA
Ethylene Glycol SCHEMBL9390653 0.94 DGKA (0.58) DGKAPAMMAPTTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4865648-A ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE KITO TSUTOMU (JP) 1989-09-12 US claimed
US-4720301-A Reversible heat sensitive recording composition PILOT INK CO., LTD. (JP) 1988-01-19 US claimed
CN-108329746-B Compounds for reducing background color in color change compositions 西甘产业股份有限公司 2022-08-02 CN disclosed
US-11225100-B2 Tunable directional color transition compositions and methods of making and using the same SEGAN INDUSTRIES, INC. (US) 2022-01-18 US disclosed
EP-2969582-B1 COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS SEGAN IND INC (US) 2021-06-02 EP disclosed
US-10570294-B2 Compounds for reducing background color in color change compositions SEGAN INDUSTRIES, INC. (US) 2020-02-25 US disclosed
US-20190204280-A1 Tunable Directional Color Transition Compositions and Methods of Making and Using the Same SEGAN INDUSTRIES, INC. 2019-07-04 US disclosed
US-20190142713-A1 Optical Evanescent Color Change Compositions and Methods of Making and Using the Same SEGAN INDUSTRIES, INC. 2019-05-16 US disclosed
CN-109476946-A Optics fadout color-changing composition and its method made and used 西甘产业股份有限公司 2019-03-15 CN disclosed
EP-3443042-A1 OPTICAL EVANESCENT COLOR CHANGE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME Segan Industries, Inc. (US) 2019-02-20 EP disclosed
US-10168307-B1 Tunable directional color transition compositions and methods of making and using the same SEGAN INDUSTRIES, INC. (US) 2019-01-01 US disclosed
EP-0677564-B1 Opaque/transparent thermochromic compositions and laminate PILOT INK CO LTD (JP) 1999-05-12 EP disclosed
EP-0827843-A1 Temperature-dependent color/transparency storing resin composition and laminate member employing the same THE PILOT INK CO., LTD. (JP) 1998-03-11 EP disclosed
US-5721059-A THERMOCHROMIC BLENDS COMPRISING AN ELECTRON-DONATING COLOR DYES, A PHENOLIC HYDROXY RADICAL AND A COMPOUND SELECTED FROM ALCOHOLS, ESTERS, KETONES AND CARBOXYLIC ACIDS IN VINYL ACETATE-VINYL CHLORIDE COPOLYMER; TOYS, COMPUTERS, OPTICS THE PILOT INK CO., LTD. (JP) 1998-02-24 US disclosed
US-5585425-A Thermochromic opaque/transparent composition, laminate member employing the same, and three-dimensional member employing said laminate member and capable of concealing and revealing the interior THE PILOT INK CO., LTD. (JP) 1996-12-17 US disclosed
US-5490956-A Thermochromic opaque composition, laminate member employing the same, and three-dimensional member employing said laminate member and capable of concealing and revealing the interior PILOT INK CO., LTD. (JP) 1996-02-13 US disclosed
EP-0677564-A2 Opaque/transparent thermochromic compositions and laminate THE PILOT INK CO., LTD. (JP) 1995-10-18 EP disclosed
EP-0595577-A2 Thermochromic opaque composition and uses thereof THE PILOT INK CO., LTD. (JP) 1994-05-04 EP disclosed
US-4865648-A ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE KITO TSUTOMU (JP) 1989-09-12 US disclosed
US-4720301-A Reversible heat sensitive recording composition PILOT INK CO., LTD. (JP) 1988-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142713-A1 Optical Evanescent Color Change Compositions and Methods of Making and Using the Same ERCC1, XPA, ERCC5 DGKA 4579/4885PAM 4424/4885MAPT 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.