Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL29353839 | 1.00 | ALOX15 (0.58) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL29111382 | 1.00 | ALOX15 (0.58) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL9683106 | 1.00 | ALOX15 (0.58) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL30849894 | 1.00 | ALOX15 (0.58) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL8053204 | 1.00 | ALOX15 (0.58) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL1656084 | 0.92 | ALOX15 (0.50) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL28077071 | 0.88 | ALOX15 (0.47) | ALOX15HSD17B10ALDH1A1TP53CYP3A4 | |
| Itaconate SCHEMBL27748501 | 0.87 | ALOX15 (0.50) | ALOX15HSD17B10LDHASRRTET2 | |
| Itaconate SCHEMBL9683112 | 0.86 | ALOX15 (0.48) | ALOX15HSD17B10TET2ALDH1A1TP53 | |
| Itaconate SCHEMBL29212156 | 0.86 | ALOX15 (0.48) | ALOX15HSD17B10TET2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740466-B1 | HIGH SENSITIVITY TO UV, VISIBLE, ANDINFRARED; FOGGING OF THE BACKGROUND IS REDUCED; CLARITY AND HIGH CONTRAST; ADDITION POLYMERIZABLE COMPOUND, AN INDOLE-PYRIMIDINETRIONE METHINE DYE, AN ANIONIC ORGANOBORON COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2004-05-25 | — | — | US | disclosed |