SCHEMBL6537244

SCHEMBL6537244

CC(C)(Br)C(=O)Oc1cccc([Si](Cl)(Cl)Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
ELANE P08246 6/20 0.39
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
RECQL P46063 1/20 0.35
ACHE P22303 1/20 0.34
POLB P06746 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809253 0.76 ESR1 (0.44) CYP3A4ELANEKMT2AMEN1LMNA
SCHEMBL809363 0.74 AKR1C3 (0.54) ELANEKMT2ALMNAGAAPOLB
SCHEMBL833149 0.74 ELANE (0.55) ELANEMAPTATML3MBTL1
SCHEMBL5597484 0.71 ELANE (0.45) CYP3A4ELANEKMT2AMEN1LMNA
SCHEMBL14361951 0.68 KMT2A (0.56) CYP3A4ELANEKMT2AMEN1LMNA
SCHEMBL10778751 0.67 ELANE (0.64) CYP3A4ELANEKMT2AMEN1LMNA
SCHEMBL13756061 0.67 TDP1 (0.55) CYP3A4KMT2AMEN1LMNACYP1A2
SCHEMBL6024449 0.67 CYP1A2 (0.53) CYP3A4ELANEKMT2ALMNACYP1A2
SCHEMBL14012162 0.66 ELANE (0.55) ELANEESR2
SCHEMBL18791204 0.66 CYP3A4 (0.67) CYP3A4ELANEPOLBESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040185238-A1 Thin film laminated with single particle layer and production method of the same FUJI PHOTO FILM CO., LTD. 2004-09-23 US disclosed
EP-1459810-A1 Thin film laminated with single particle layer and production method of the same FUJI PHOTO FILM CO., LTD. (JP) 2004-09-22 EP disclosed