SCHEMBL14012162

SCHEMBL14012162

CC(C)(Br)C(=O)Oc1ccc(-c2ccc(OC(=O)C(C)(C)Br)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ELANE P08246 16/20 0.55
HSD17B10 Q99714 1/20 0.46
KIF11 P52732 1/20 0.43
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437118 0.85 ELANE (0.53) ELANE
SCHEMBL13998362 0.84 ELANE (0.76) ELANEHSD17B10
SCHEMBL28985550 0.83 ELANE (0.52) ELANE
SCHEMBL3308809 0.83 ELANE (0.52) ELANE
SCHEMBL1197149 0.83 ELANE (0.52) ELANEESR2
SCHEMBL10778751 0.83 ELANE (0.64) ELANE
SCHEMBL833149 0.83 ELANE (0.55) ELANEHSD17B10
SCHEMBL6942993 0.82 ADRB2 (0.43) ELANE
SCHEMBL22607186 0.82 ELANE (0.56) ELANEHSD17B10
SCHEMBL30672797 0.82 ELANE (0.50) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470762-B2 Living radical polymerization of acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-12-30 US disclosed
US-7345127-B2 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-03-18 US disclosed
US-20080039601-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA 2008-02-14 US disclosed