Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537251 | 0.87 | LPAR3 (0.49) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL6537591 | 0.87 | LPAR3 (0.49) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL6935159 | 0.82 | PPARD (0.47) | — | |
| SCHEMBL9257620 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 | |
| SCHEMBL11671731 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 | |
| SCHEMBL11752839 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 | |
| SCHEMBL11671572 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 | |
| SCHEMBL11668838 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 | |
| SCHEMBL7540607 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 | |
| SCHEMBL3815174 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082549-A1 | Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections | JOMAA HASSAN (DE) | 2004-04-29 | — | — | US | disclosed |
| US-6680308-B1 | ADMINISTERING N-(FORMYL OR ACETYL)-N-HYDROXYLAMINO)-ALKYLPHOSPHONIC ACID DERIVATIVE AS VIRICIDE, PARASITICIDE OR FUNGICIDE | BIOAGENCY AG (DE) | 2004-01-20 | — | — | US | disclosed |
| EP-1071409-B1 | USE OF ORGANOPHOSPHORIC COMPOUNDS FOR THE THERAPEUTIC AND PREVENTATIVE TREATMENT OF INFECTIONS | BIOAGENCY AG (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-1071409-A2 | USE OF ORGANOPHOSPHORIC COMPOUNDS FOR THE THERAPEUTIC AND PREVENTATIVE TREATMENT OF INFECTIONS | Jomaa, Hassan (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-2000017212-A1 | ORGANOPHOSPHOROUS COMPOUNDS AND USE THEREOF | JOMAA HASSAN (DE) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999052515-A2 | USE OF ORGANOPHOSPHORIC COMPOUNDS FOR THE THERAPEUTIC AND PREVENTATIVE TREATMENT OF INFECTIONS | HASSAN JOMAA (DE) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082549-A1 | Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections | PON1, DDT, GPX1 | LPAR3 2882/4885LPAR2 3330/4885LPAR1 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.