SCHEMBL653748

SCHEMBL653748

O=C(O)c1ccc(Cl)cc1C(=O)O.[Na]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.68
ALDH1A1 P00352 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
TP53 P04637 1/20 0.68
CASP1 P29466 1/20 0.68
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
KDM4E B2RXH2 2/20 0.53
HSD17B10 Q99714 1/20 0.53
MYC P01106 2/20 0.52
NR4A1 P22736 2/20 0.52
F7 P08709 1/20 0.50
F3 P13726 1/20 0.50
ACLY P53396 1/20 0.50
GRIK1 P39086 3/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SRD5A2 P31213 1/20 0.48
AKR1C4 P17516 1/20 0.48
AKR1C3 P42330 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31620984 1.00 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
SCHEMBL30411921 1.00 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
SCHEMBL1000440 0.98 ALDH1A1 (0.71) TSHRALDH1A1SMN1; SMN2TP53CASP1
Water SCHEMBL29236524 0.95 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
SCHEMBL28932511 0.95 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
SCHEMBL27691807 0.95 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
Hydrochloric Acid SCHEMBL10902309 0.95 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
SCHEMBL653746 0.95 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
Hydrochloric Acid SCHEMBL29119588 0.95 TSHR (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1
SCHEMBL8248300 0.86 ALDH1A1 (0.68) TSHRALDH1A1SMN1; SMN2TP53CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118649643-B Continuous chlorination reaction device and method for sodium 4-chlorophthalite 河北彩客新材料科技股份有限公司 2024-11-29 CN claimed
CN-118649643-A Continuous chlorination reaction device and method for sodium 4-chlorophthalite 河北彩客新材料科技股份有限公司 2024-09-17 CN claimed
CN-114621078-B Preparation method of 4-chlorophthalic acid monosodium salt and 4-chlorophthalic anhydride 河北海力恒远新材料股份有限公司 2023-10-31 CN claimed
CN-219272783-U Batching device for producing 4-chlorophthalic acid monosodium salt 河北泽硕药业科技有限公司 2023-06-30 CN claimed
CN-116332747-A Method for preparing biphenyl tetracarboxylic acid based on palladium-carbon catalyst and activation method of palladium-carbon catalyst 河北东丽新材料有限公司 2023-06-27 CN claimed
CN-115995598-A Multifunctional sodium battery electrolyte additive and application thereof 中国科学院物理研究所 2023-04-21 CN claimed
CN-114478234-B Refining method of 4-chlorophthalic acid monosodium salt crude product 河北海力恒远新材料股份有限公司 2023-03-31 CN claimed
CN-115010601-B Method for treating 3,3',4,4' -biphenyl tetracarboxylic acid production wastewater 河北海力香料股份有限公司 2022-11-22 CN claimed
CN-114853705-A Method for preparing chlorophthalic anhydride by recovering 4-chlorophthalic acid monosodium salt reaction mother liquor 河北海力香料股份有限公司 2022-08-05 CN claimed
CN-111620769-B Method for preparing 3,3 ', 4, 4' -biphenyl tetracarboxylic dianhydride 南通汇顺化工有限公司 2022-06-28 CN claimed
CN-114621078-A Preparation method of 4-chlorophthalic acid monosodium salt and 4-chlorophthalic anhydride 河北海力香料股份有限公司 2022-06-14 CN claimed
CN-114478234-A Refining method of 4-chlorophthalic acid monosodium salt crude product 河北海力香料股份有限公司 2022-05-13 CN claimed
CN-111620769-A Method for preparing 3,3 ', 4, 4' -biphenyl tetracarboxylic dianhydride 南通汇顺化工有限公司 2020-09-04 CN claimed
CN-110563678-A Preparation method of 3,3',4,4' -biphenyl tetracarboxylic dianhydride 上海固创化工新材料有限公司 2019-12-13 CN claimed
CN-121471082-A Preparation method of high-yield 4-chlorophthalic acid monosodium salt 宁晋县海泰化工有限公司 2026-02-06 CN disclosed
CN-223221453-U Discharging anti-blocking device of 4-chlorophthalic acid sodium reaction kettle 河北彩客新材料科技股份有限公司 2025-08-15 CN disclosed
CN-223221453-U Discharging anti-blocking device of 4-chlorophthalic acid sodium reaction kettle 河北彩客新材料科技股份有限公司 2025-08-15 CN disclosed
US-5552414-A 1-(1H-indolyloxyalkyl)-4-(heteroaryl) piperidines and related compounds useful as antipsychotics and analgesics HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-09-03 US disclosed
US-5550130-A ANTIPSYCHOTIC AGENTS, ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-08-27 US disclosed
WO-1995011680-A1 HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1995-05-04 WO disclosed