Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538181 | 0.92 | MEN1 (0.34) | MEN1KMT2ANPC1LCKMAPK14 | |
| SCHEMBL6537953 | 0.89 | PTGES (0.37) | MEN1KMT2ANPC1LCKMAPK14 | |
| SCHEMBL6537474 | 0.87 | LCK (0.36) | MEN1KMT2ANPC1LCKMAPK14 | |
| SCHEMBL6538154 | 0.82 | MAPT (0.38) | NPC1LCKMAPK14KDM4ETSHR | |
| SCHEMBL8477159 | 0.82 | TYK2 (0.38) | MEN1KMT2ATSHRHDAC3NCOR1 | |
| SCHEMBL6537657 | 0.80 | PTGES (0.37) | MEN1KMT2ANPC1LCKMAPK14 | |
| SCHEMBL6537963 | 0.80 | PTGES (0.37) | MEN1KMT2ALCKMAPK14JAK2 | |
| SCHEMBL6537499 | 0.79 | KMT2A (0.35) | MEN1KMT2ANPC1LCKMAPK14 | |
| SCHEMBL6537705 | 0.78 | MEN1 (0.37) | MEN1KMT2ANPC1LCKMAPK14 | |
| SCHEMBL6537516 | 0.76 | SMN1; SMN2 (0.34) | MEN1KMT2ATSHRHDAC3NCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |