Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537657 | 0.84 | PTGES (0.37) | ALDH1A1HTTTSHRKDM4EHSD17B10 | |
| SCHEMBL6537602 | 0.84 | PTGES (0.39) | HTTHSD17B10KMT2APTGESPOLB | |
| SCHEMBL6537953 | 0.83 | PTGES (0.37) | HTTTSHRKDM4EHSD17B10KMT2A | |
| SCHEMBL6537695 | 0.83 | PTGES (0.44) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL6538297 | 0.83 | MEN1 (0.41) | ALDH1A1NPSR1HTTKDM4EMAPT | |
| SCHEMBL6537678 | 0.82 | PTGES (0.42) | ALDH1A1HTTKDM4EKMT2APTGES | |
| SCHEMBL6537759 | 0.82 | PTGES (0.44) | ALDH1A1HTTLMNATSHRKDM4E | |
| SCHEMBL6537966 | 0.82 | CYP3A4 (0.45) | HTTKMT2APTGESPOLBEPHB3 | |
| SCHEMBL6538012 | 0.81 | PTGES (0.42) | ALDH1A1HTTKDM4EKMT2APTGES | |
| SCHEMBL6538208 | 0.80 | PTGES (0.42) | ALDH1A1HTTKDM4EKMT2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |