SCHEMBL6537762

SCHEMBL6537762

CCC(C)c1c(N)cc2c(c1N)C(C)(C)CC2

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.36
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937299 0.86 LIMK1 (0.31)
SCHEMBL6538363 0.79 EEF2K (0.38) EEF2KUSP2ALDH1A1GAAPKM
SCHEMBL6537879 0.76 LIMK1 (0.31)
SCHEMBL6538028 0.74 LIMK1 (0.30)
SCHEMBL6537903 0.74 LIMK1 (0.33) ALOX15
SCHEMBL6538319 0.73 ESR1 (0.31) ESR1ESR2
SCHEMBL6538357 0.72 SKP2 (0.37) HPGD
SCHEMBL6538093 0.71 LIMK1 (0.32)
SCHEMBL6538117 0.66 LIMK1 (0.35)
SCHEMBL6537985 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4987261-A Diaminoindane derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1991-01-22 US claimed
EP-1225192-B1 POLYIMIDES AND POLYAMIC ACIDS MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6599675-B2 Useful for application of photoresist, as an insulation film; heat resistance, mechanical properties and adhesion property MITSUI CHEMICALS, INC. (JP) 2003-07-29 US disclosed
US-20020182536-A1 Polyimides and polyamic acids MITSUI CHEMICALS, INC. (JP) 2002-12-05 US disclosed
EP-1225192-A1 POLYIMIDES AND POLYAMIC ACIDS Mitsui Chemicals, Inc. (JP) 2002-07-24 EP disclosed
US-4987261-A Diaminoindane derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1991-01-22 US disclosed